Publicaciones recientes

Garcés M, Guijarro IM, Ritchie DL, Badiola JJ, Monzón M. Novel morphological glial alterations in the spectrum of prion disease types: A focus on common findings. Pathogens. 2021 May 13;10(5):596. doi: 10.3390/pathogens10050596

Toledano-Díaz A, Álvarez MI, Rodríguez JJ, Badiola JJ, Monzón M, Toledano A. Reflections on cerebellar neuropathology in classical scrapie. Biomolecules. 2021 Apr 28;11(5):649. doi: 10.3390/biom11050649.

García-Mendívil L, Mediano D.R, Hernaiz A, Sanz-Rubio D, Vázquez FJ, Marín B, López-Pérez O, Otero A, Badiola JJ, Zaragoza P, Ordovás L, Bolea R, Martín-Burriel I. Effect of scrapie prion infection in ovine bone marrow-derived mesenchymal stem cells and ovine mesenchymal stem cell-derived neurons. Animals (Basel) 2021 Apr 15; 11(4):1137. doi: 10.3390/ani11041137.

Barrio T, Vidal E, Betancor M, Otero A, Martín-Burriel I, Monzón M, Monleón E, Pumarola M, Badiola JJ, Bolea R. Evidence of p75 neurotrophin receptor involvement in the central nervous system pathogenesis of classical scrapie in sheep and a transgenic mouse model. Int J Mol Sci. 2021 Mar 8; 22(5):2714. doi: 10.3390/ijms22052714.

Acín C, Bolea R, Monzón M, Monleón E, Moreno B, Filali H, Marín B, Sola D, Betancor M, Guijarr IM, García M, Vargas A, Badiola JJ. Classical and atypical scrapie in sheep and goats. Review on the etiology, genetic factors, pathogenesis, diagnosis, and control measures of both diseases. Animals (Basel) 2021 Mar 4; 11(3):691. Mar 4. doi: 10.3390/ani11030691.

Guijarro IM, Garcés M, Andrés-Benito P, Marín B, Otero A, Barrio T, Carmona M, Ferrer I, Badiola JJ, Monzón M. Neuroimmune response mediated by cytokines in natural scrapie after chronic dexamethasone treatment. Biomolecules. 2021 Feb 2; 11(2):204. doi: 10.3390/biom11020204.

Otero A, Betancor M, Eraña H, Fernández N, Lucas JJ, Badiola JJ, Castilla J Bolea R. Prion-associated neurodegeneration causes both endoplasmic reticulum stress and proteasome impairment in a murine model of spontaneous disease. Int. J. Mol. Sci. 2021, Jan 5;22(1):465. doi:10.3390/ijms22010465

Mata E, Farrell D, Ma R, Uranga S, Gomez AB, Monzon M, Badiola J, Anel A, Gonzalo-Asensio J, Martin C, Gordon SV, Aguiló N. Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference. PLoS Pathog. 2020 Dec; 16(12): e1009061. doi: 10.1371/journal.ppat.1009061.

López-Pérez O, Badiola JJ, Bolea R, Ferrer I, Llorens F, Martín-Burriel I. An update on autophagy in prion diseases. Front Bioeng Biotechnol. 2020; 8: 975. Published online 2020 Aug 27. doi: 10.3389/fbioe.2020.00975

Guijarro IM, Garcés M, Marín B, Otero A, Barrio T, Badiola JJ, Monzón M. Neuroinmune response in natural preclinical scrapie after dexamethasone treatment. Int J Mol Sci. 2020 Aug; 21(16): 5779. doi: 10.3390/ijms21165779

Aguilo N, Uranga S, Mata E, Tarancon R, Gómez AB, Marinova D, Otal I, Monzón M, Badiola J, Montenegro D, Puentes E, Rodríguez E, Vervenne RAW, Sombroek CC, Verreck FAW, Martín C. Respiratory immunization with a whole cell inactivated vaccine induces functional mucosal immunoglobulins against tuberculosis in mice and non-human primates. Front. Microbiol. 2020 June 18.11:1339. doi: 10.3389/fmicb.2020.01339. eCollection 2020.

Toivonen JN, Sanz-Rubio D, López-Pérez O, Marín-Moreno A, Bolea R, Osta R, Badiola JJ, Zaragoza P, Espinosa JC, Torres JM, Martín-Burriel I. MicroRNA alteration in a Tg501 mouse model of prion disease. Biomolecules. 2020 Jun; 10(6): 908. Published online 2020 Jun 15. doi: 10.3390/biom10060908