Publicaciones recientes

Vidal E, Sánchez-Martín MA, Eraña H, Lázaro SP, Pérez-Castro MA, Otero A, Charco JM, Marín B, López-Moreno R, Díaz-Domínguez CM, Geijo M, Ordóñez M, Cantero G, di Bari M, Lorenzo NL, Pirisinu L, d’Agostino C, Torres JM, Béringue V, Telling G, Badiola JJ, Pumarola M, Bolea R, Nonno R, Requena JR, Castilla J. Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model. Acta Neuropathol Commun. 2022 Dec 13;10(1):179. doi: 10.1186/s40478-022-01477-7.

Otero A, Castilla J,Barrio T ,Eraña H, Charco JM, Betancor M, Diaz-Dominguez CM, Marin M, Andreoletti O, Torres JM, Quinghong K , Badiola JJ, Bolea R. Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy» PLoS Pathogen 2022 Oct 7;18(10):e1010900. doi: 10.1371/journal.ppat.1010900.

Betancor M, Pérez-Lázaro S, Otero A, Marín B, Martín-Burriel I, Blennow K, Badiola JJ, Zetterberg H. Bolea R. Neurogranin and neurofilament light chain as preclinical biomarkers in scrapie. Int J Mol Sci 2022, 23,7182. doi.org/10.3390/ ijms23137182.

García-Martínez, M, Cortez LM, Otero A, Betancor M, Serrano-Pérez B, Bolea R, Badiola JJ, Garza MC. Distinctive toll-like receptors gene expression and glial response in different brain regions of natural scrapie. Int J Mol Sci. 23 – 7, pp.3579 [24 pp.]. 2022. doi: 10.3390/ijms23073579.

Hernaiz A, Sanz A, Sentre S, Ranera B, Lopez-Pérez O, Zaragoza P, Badiola JJ, Filali H, Bolea R, Toivonen JM, Martín-Burriel I. Genome-Wide methylation profiling in the thalamus of the Scrapie sheep. Front Vet Sci. 2022 Feb 16; 9:824677. doi: 10.3389/fvets.2022.824677

Badiola JJ, Otero A, Sevilla E, Marín B, García Martínez M, Betancor, Sola D, Pérez-Lázaro S, Lozada J, Velez C, Chiner-Oms A, Comas I, Cancino-Muñoz I, Monleón E, Monzón M, Acín C, Bolea R, Moreno B. SARS-CoV-2 outbreak on a spanish mink farm: Epidemiological, molecular, and pathological studies. Front. Vet. Sci., 21 January 2022, doi.org/10.3389/fvets.2021.805004.

López M, Chiner-Oms A, García de Viedma D et al. The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variants. Nature Genet 53, 1405–1414 (2021). doi.org/10.1038/s41588-021-00936-6.

Mata E, Tarancon R, Guerreo C, Moreo E, Moreau F, Uranga S,Gomez AB, Marinova D, Domenech M, Gonzalez-Camacho F, Monzon M, Badiola J, Dominguez-Andrés J, Yuste J, Anel A, Peixoto A, Martín C, Aguilo N. Pulmonary BCG induces lung-resident macrophage activation and confers long-term protection against tuberculosis. Sci Immunol 2021 Sep 24;6(63): eabc2934. doi: 10.1126/sciimmunol.abc2934.

Betancor M, Moreno-Martínez L, López-Pérez Ó, Otero A, Hernaiz A, Barrio T, Badiola JJ, Osta R, Bolea R, Martín-Burriel I. Therapeutic assay with the non-toxic C-Terminal fragment of tetanus toxin (TTC) in transgenic murine models of prion disease. Mol Neurobiol. 2021 Oct; 58(10):5312-5326. doi: 10.1007/s12035-021-02489-5. Epub 2021 Jul 20.

Marín B, Otero A, Lugan S, Espinosa JC, Marín-Moreno A, Vidal E, Hedman C, Romero A, Pumarola M, Badiola JJ, Torres JM, Andréoletti O, Bolea R. Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie. Sci Rep. 2021 Aug 31;11(1):17428. doi: 10.1038/s41598-021-96818-2

Castro A, Diaz MC, Mendoza C, Moreno B, Zanucci C, Carrica M, Lendez P, Carri J, Ghezzi M, Badiola JJ, Barbeito C. Patterns of proliferation and cell differentiation during hepatic ontogeny in the alpaca. Tissue and Cell. 2021 Aug; 71:101589. doi: 10.1016/j.tice.2021.101589.

López-Pérez Ó, Sanz-Rubio D, Hernaiz A, Betancor M, Otero A, Castilla J, Andréoletti O, Badiola JJ, Zaragoza P, Bolea R, Toivonen JM, Martín-Burriel I. Cerebrospinal fluid and plasma small extracellular vesicles and miRNAs as biomarkers for prion diseases. Int J Mol Sci. 2021 Jun 25;22(13):6822. doi: 10.3390/ijms22136822